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  9. Generate single-mutants (aevol_post_mutagenesis)

Generate single-mutants (aevol_post_mutagenesis)

Mutagenesis generates a configurable number of single mutants for a specified type of mutations, on a given genome. From this it computes the mutational robustness and evolvability of this genome and, using the –full option, samples the DFE (Distribution of Fitness Effect) of the specified type of mutation on the specified genome.

Usage of aevol_post_mutagenesis (output of aevol_post_mutagenesis --help) 

aevol_post_mutagenesis:
generate single-mutants of the provided individuals, using the requested mutation type; output fitness effect stats thereof.

Usage : aevol_post_mutagenesis -h or --help
   or : aevol_post_mutagenesis -V or --version
   or : aevol_post_mutagenesis [OPTIONS] FASTA_FILE PARAM_FILE MUTATION_TYPE

   FASTA_FILE:    sequence(s) of the individual(s) of interest
   PARAM_FILE:    parameters to be used for the experiment
   MUTATION_TYPE: type of mutations to generate. Possible values:
     'SWITCH', 'SMALL_INSERTION', 'SMALL_DELETION' (local mutations)
     'DUPLICATION', 'DELETION', 'TRANSLOCATION', 'INVERSION' (rearrangements)

Options
  -h, --help
	print this help, then exit
  -V, --version
	print version number, then exit
  -n, --nb-offspring NB_OFFSPRING
	number of offspring to be generated for each individual
  -v, --verbose
	be verbose
  --full
	require additional output containing the Fitness Effect of each replication
  --seed PRNG_SEED
	seed to be used for prng initialization